Linker Information
General Information of This Linker
| Linker ID |
LIN0WXPTP
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|---|---|---|---|---|---|---|
| Linker Name |
Disulfide linker 8
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| Linker Type |
Thiol-sensitive linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C16H16ClN3O4S2
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| Isosmiles |
CC(COC(=O)Nc1ccc(CCl)cc1)SSc1ccc([N+](=O)[O-])cn1
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| InChI |
InChI=1S/C16H16ClN3O4S2/c1-11(25-26-15-7-6-14(9-18-15)20(22)23)10-24-16(21)19-13-4-2-12(8-17)3-5-13/h2-7,9,11H,8,10H2,1H3,(H,19,21)
|
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| InChIKey |
YVRHDGUYPQMPMN-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
413.908
|
Polar area
|
94.36
|
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|
Complexity
|
26
|
xlogp Value
|
5.1061
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Heavy Count
|
26
|
Rot Bonds
|
8
|
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|
Hbond acc
|
7
|
Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker
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