Linker Information
General Information of This Linker
| Linker ID |
LIN0WWZEY
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| Linker Name |
Mc-PEG4-EvcPAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C41H66N8O18
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| Isosmiles |
CC([C@H](NC([C@@H](NC(CCOCCOCCOCCOCCNC(CNC(CCC(O)=O)=O)=O)=O)CCC(O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC1CC=C(C=C1)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C41H66N8O18/c1-26(2)36(39(59)48-29(4-3-14-44-40(42)60)37(57)46-28-7-5-27(6-8-28)25-67-41(61)62)49-38(58)30(9-11-34(53)54)47-32(51)13-16-63-18-20-65-22-23-66-21-19-64-17-15-43-33(52)24-45-31(50)10-12-35(55)56/h5-7,26,28-30,36H,3-4,8-25H2,1-2H3,(H,43,52)(H,45,50)(H,46,57)(H,47,51)(H,48,59)(H,49,58)(H,53,54)(H,55,56)(H,61,62)(H3,42,44,60)/t28?,29-,30-,36-/m0/s1
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| InChIKey |
IEVFTOVOZXCRRG-IQAKKFJESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
959.017
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Polar area
|
387.77
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Complexity
|
1605.653743
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xlogp Value
|
-1.9705
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Heavy Count
|
67
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Rot Bonds
|
37
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Hbond acc
|
15
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker