Linker Information
General Information of This Linker
| Linker ID |
LIN0WVKSE
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| Linker Name |
CN112341521B+Linker11
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C48H74N10O18S
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| Isosmiles |
CS(C1=NC(CN2CCCC(N=N3)=CN3CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@@H](CCCCN)C(NC4=CC=C(COC(O)=O)C=C4)=O)=O)=O)=C(C2=O)C=N1)(=O)=O
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| InChI |
InChI=1S/C48H74N10O18S/c1-77(65,66)47-51-31-40-42(54-47)33-57(46(40)62)13-4-5-39-32-58(56-55-39)14-16-68-18-20-70-22-24-72-26-28-74-30-29-73-27-25-71-23-21-69-19-17-67-15-12-50-43(59)35-75-36-44(60)53-41(6-2-3-11-49)45(61)52-38-9-7-37(8-10-38)34-76-48(63)64/h7-10,31-32,41H,2-6,11-30,33-36,49H2,1H3,(H,50,59)(H,52,61)(H,53,60)(H,63,64)/t41-/m0/s1
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| InChIKey |
DAYAEKQIJOFUKD-RWYGWLOXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1111.239
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Polar area
|
353.86
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Complexity
|
2207.668393
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xlogp Value
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-0.2271
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Heavy Count
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77
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Rot Bonds
|
45
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Hbond acc
|
23
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker