Linker Information
General Information of This Linker
| Linker ID |
LIN0WUPSL
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| Linker Name |
CN112341521B+Linker24
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C23H35N7O8S
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| Isosmiles |
CC([C@H](NC(CCCCN1CC2=C(C=NC(S(C)(=O)=O)=N2)C1=O)=O)C(N[C@@H](CCCNC(N)=O)C(O)=O)=O)C
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| InChI |
InChI=1S/C23H35N7O8S/c1-13(2)18(19(32)27-15(21(34)35)7-6-9-25-22(24)36)29-17(31)8-4-5-10-30-12-16-14(20(30)33)11-26-23(28-16)39(3,37)38/h11,13,15,18H,4-10,12H2,1-3H3,(H,27,32)(H,29,31)(H,34,35)(H3,24,25,36)/t15-,18-/m0/s1
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| InChIKey |
WOCCGWPDOQSQOG-YJBOKZPZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
569.641
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Polar area
|
230.85
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Complexity
|
1146.418767
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xlogp Value
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-0.8351
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Heavy Count
|
39
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Rot Bonds
|
15
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Hbond acc
|
9
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker