Linker Information
General Information of This Linker
| Linker ID |
LIN0WUJQB
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| Linker Name |
MC-Ala-Ala-RG-2
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H46N6O9
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| Isosmiles |
O=C(N[C@@H](C)C(NC1=CC=C(COC(NC(C)C2=CC=CC=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C36H46N6O9/c1-22(2)32(40-29(43)13-7-6-10-20-42-30(44)18-19-31(42)45)34(47)37-24(4)33(46)39-26-16-14-25(15-17-26)21-51-35(48)38-23(3)27-11-8-9-12-28(27)41(5)36(49)50/h8-9,11-12,14-19,22-24,32H,6-7,10,13,20-21H2,1-5H3,(H,37,47)(H,38,48)(H,39,46)(H,40,43)(H,49,50)/t23?,24-,32-/m0/s1
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| InChIKey |
CEIRIKRICRQDDY-YYONYHEJSA-N
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| Pharmaceutical Properties |
Molecule Weight
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706.797
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Polar area
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203.55
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Complexity
|
1547.817311
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xlogp Value
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3.8576
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Heavy Count
|
51
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Rot Bonds
|
17
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Hbond acc
|
8
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker