Linker Information
General Information of This Linker
| Linker ID |
LIN0WTXPV
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| Linker Name |
CN113549127A-ADC-14-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H45N7O8S
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| Isosmiles |
CC(C)[C@@H](NC(CCCCCOCCOCCCN1C(C(C=NC(S)=N2)=C2C1)=O)=O)C(N[C@H](C(O)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C28H45N7O8S/c1-18(2)23(24(37)32-20(26(39)40)8-6-10-30-27(29)41)34-22(36)9-4-3-5-12-42-14-15-43-13-7-11-35-17-21-19(25(35)38)16-31-28(44)33-21/h16,18,20,23H,3-15,17H2,1-2H3,(H,32,37)(H,34,36)(H,39,40)(H3,29,30,41)(H,31,33,44)/t20-,23+/m0/s1
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| InChIKey |
GKEYKEQWURVYQG-NZQKXSOJSA-N
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| Pharmaceutical Properties |
Molecule Weight
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639.776
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Polar area
|
215.17
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Complexity
|
1061.509292
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xlogp Value
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0.8635
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Heavy Count
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44
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Rot Bonds
|
22
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Hbond acc
|
10
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker