Linker Information
General Information of This Linker
| Linker ID |
LIN0WTIJZ
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| Linker Name |
AU2023306656A1 ADC1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C18H27N3O6
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| Isosmiles |
C[C@H](NC([C@H](C(C)C)NC(CCCCCN1C(C=CC1=O)=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C18H27N3O6/c1-11(2)16(17(25)19-12(3)18(26)27)20-13(22)7-5-4-6-10-21-14(23)8-9-15(21)24/h8-9,11-12,16H,4-7,10H2,1-3H3,(H,19,25)(H,20,22)(H,26,27)/t12-,16-/m0/s1
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| InChIKey |
GSWKJIWKGSPISH-LRDDRELGSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
381.429
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Polar area
|
132.88
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Complexity
|
577.5278502
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xlogp Value
|
0.2019
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Heavy Count
|
27
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Rot Bonds
|
11
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Hbond acc
|
5
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker