Linker Information
General Information of This Linker
| Linker ID |
LIN0WRQGQ
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| Linker Name |
T-102 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H37N5O15S
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| Isosmiles |
CN(CCOCCN1C=C(N=N1)CCOCCN(C(C=C2)=O)C2=O)C(C3=CC=C(O[C@H]4[C@@H](O)[C@@H](O)[C@@H](O)[C@H](O4)CO)C(OS(O)(=O)=O)=C3)=O
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| InChI |
InChI=1S/C28H37N5O15S/c1-31(7-11-45-12-8-32-15-18(29-30-32)6-10-44-13-9-33-22(35)4-5-23(33)36)27(40)17-2-3-19(20(14-17)48-49(41,42)43)46-28-26(39)25(38)24(37)21(16-34)47-28/h2-5,14-15,21,24-26,28,34,37-39H,6-13,16H2,1H3,(H,41,42,43)/t21-,24+,25+,26+,28-/m1/s1
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| InChIKey |
XPABJMFOAOOYAQ-AWTHHPGASA-N
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| Pharmaceutical Properties |
Molecule Weight
|
715.691
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Polar area
|
269.84
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Complexity
|
1511.694221
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xlogp Value
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-3.0887
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Heavy Count
|
49
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Rot Bonds
|
18
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Hbond acc
|
17
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker