Linker Information
General Information of This Linker
| Linker ID |
LIN0WRFOD
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|---|---|---|---|---|---|---|
| Linker Name |
IG-L-63 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C12H9ClN2O4
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| Isosmiles |
CC1=C(N2C(C=CC2=O)=O)C=C(NC(O)=O)C=C1Cl
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| InChI |
InChI=1S/C12H9ClN2O4/c1-6-8(13)4-7(14-12(18)19)5-9(6)15-10(16)2-3-11(15)17/h2-5,14H,1H3,(H,18,19)
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| InChIKey |
BZIJFWCOZTUIJE-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
280.667
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Polar area
|
86.71
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Complexity
|
578.7094799
|
xlogp Value
|
2.16772
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Heavy Count
|
19
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Rot Bonds
|
2
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Hbond acc
|
3
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker
