General Information of This Linker
Linker ID
LIN0WRFOD
Linker Name
IG-L-63 linker
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C12H9ClN2O4
Isosmiles
CC1=C(N2C(C=CC2=O)=O)C=C(NC(O)=O)C=C1Cl
InChI
InChI=1S/C12H9ClN2O4/c1-6-8(13)4-7(14-12(18)19)5-9(6)15-10(16)2-3-11(15)17/h2-5,14H,1H3,(H,18,19)
InChIKey
BZIJFWCOZTUIJE-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
280.667
Polar area
86.71
Complexity
578.7094799
xlogp Value
2.16772
Heavy Count
19
Rot Bonds
2
Hbond acc
3
Hbond Donor
2
Each Antibody-drug Conjugate Related to This Linker