Linker Information
General Information of This Linker
| Linker ID |
LIN0WQYOV
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| Linker Name |
CN113549127A-ADC-9-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C42H70N8O13S
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| Isosmiles |
OC([C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN1C=C(N=N1)CCCC#CC(C=N2)=CN=C2SCCC)=O)=O)CCCCN)=O
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| InChI |
InChI=1S/C42H70N8O13S/c1-2-30-64-42-45-31-36(32-46-42)8-4-3-5-9-37-33-50(49-48-37)13-15-56-17-19-58-21-23-60-25-27-62-29-28-61-26-24-59-22-20-57-18-16-55-14-12-44-39(51)34-63-35-40(52)47-38(41(53)54)10-6-7-11-43/h31-33,38H,2-3,5-7,9-30,34-35,43H2,1H3,(H,44,51)(H,47,52)(H,53,54)/t38-/m0/s1
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| InChIKey |
CKRJEBSCOIZBAO-LHEWISCISA-N
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| Pharmaceutical Properties |
Molecule Weight
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927.132
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Polar area
|
261.08
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Complexity
|
1449.132365
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xlogp Value
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0.9086
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Heavy Count
|
64
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Rot Bonds
|
43
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Hbond acc
|
19
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker