Linker Information
General Information of This Linker
| Linker ID |
LIN0WOGXH
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| Linker Name |
B1-b linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H45N7O11
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(OCC3=CC=C([N+]([O-])=O)C=C3)=O)C=C2)=O)=O)C
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| InChI |
InChI=1S/C36H45N7O11/c1-23(2)32(41-29(44)8-4-3-5-20-42-30(45)17-18-31(42)46)34(48)40-28(7-6-19-38-35(37)49)33(47)39-26-13-9-24(10-14-26)21-53-36(50)54-22-25-11-15-27(16-12-25)43(51)52/h9-18,23,28,32H,3-8,19-22H2,1-2H3,(H,39,47)(H,40,48)(H,41,44)(H3,37,38,49)/t28-,32-/m0/s1
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| InChIKey |
XVZFXVWVNVHRDR-IUDBTDONSA-N
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| Pharmaceutical Properties |
Molecule Weight
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751.794
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Polar area
|
258.47
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Complexity
|
1610.300625
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xlogp Value
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2.9462
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Heavy Count
|
54
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Rot Bonds
|
21
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Hbond acc
|
11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker