Linker Information
General Information of This Linker
| Linker ID |
LIN0WMMTD
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| Linker Name |
CN113549127A-ADC-7-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H47N9O8S
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| Isosmiles |
OC([C@@H](NC(COCC(NCCOCCOCCN1C=C(N=N1)CCCN2C(C(C=NC(SCCC)=N3)=C3C2)=O)=O)=O)CCCCN)=O
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| InChI |
InChI=1S/C30H47N9O8S/c1-2-16-48-30-33-17-23-25(35-30)19-38(28(23)42)10-5-6-22-18-39(37-36-22)11-13-46-15-14-45-12-9-32-26(40)20-47-21-27(41)34-24(29(43)44)7-3-4-8-31/h17-18,24H,2-16,19-21,31H2,1H3,(H,32,40)(H,34,41)(H,43,44)/t24-/m0/s1
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| InChIKey |
NEYRIXFRSJWRAV-DEOSSOPVSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
693.828
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Polar area
|
226.01
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Complexity
|
1246.575957
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xlogp Value
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0.0232
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Heavy Count
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48
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Rot Bonds
|
26
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Hbond acc
|
14
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker