Linker Information
General Information of This Linker
| Linker ID |
LIN0WKUVU
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| Linker Name |
IG-L-19 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C54H88N6O23
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCCC[C@H](NC(COCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)C(N[C@@H](C)C(N[C@@H](C)C(NC2=CC=C(COC(O)=O)C=C2)=O)=O)=O
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| InChI |
InChI=1S/C54H88N6O23/c1-42(51(65)56-43(2)52(66)58-45-9-7-44(8-10-45)40-83-54(68)69)57-53(67)46(59-48(62)41-82-39-38-72-17-14-55-47(61)13-15-60-49(63)11-12-50(60)64)6-4-5-16-71-20-21-74-24-25-76-28-29-78-32-33-80-36-37-81-35-34-79-31-30-77-27-26-75-23-22-73-19-18-70-3/h7-12,42-43,46H,4-6,13-41H2,1-3H3,(H,55,61)(H,56,65)(H,57,67)(H,58,66)(H,59,62)(H,68,69)/t42-,43-,46-/m0/s1
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| InChIKey |
GVMLBDFLJKCQMU-MDGKGBRESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1189.317
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Polar area
|
349.4
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Complexity
|
1870.307866
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xlogp Value
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-0.2389
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Heavy Count
|
83
|
Rot Bonds
|
55
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Hbond acc
|
22
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker