Linker Information
General Information of This Linker
| Linker ID |
LIN0WHCVX
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| Linker Name |
Trastuzumab-LD7-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H60N6O13
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| Isosmiles |
CCN(C(OCC1=CC=C(NC([C@H](C)NC([C@@H](NC(OCCOCCOCCOCCOC)=O)C(C)C)=O)=O)C=C1)=O)C.O=C(N2CCOCCN)C=CC2=O
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| InChI |
InChI=1S/C29H48N4O10.C8H12N2O3/c1-7-33(5)29(37)43-20-23-8-10-24(11-9-23)31-26(34)22(4)30-27(35)25(21(2)3)32-28(36)42-19-18-41-17-16-40-15-14-39-13-12-38-6;9-3-5-13-6-4-10-7(11)1-2-8(10)12/h8-11,21-22,25H,7,12-20H2,1-6H3,(H,30,35)(H,31,34)(H,32,36);1-2H,3-6,9H2/t22-,25-;/m0./s1
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| InChIKey |
QLBOOGXPYFLFIT-YSCHMLPRSA-N
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| Pharmaceutical Properties |
Molecule Weight
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796.916
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Polar area
|
235.62
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Complexity
|
1275.748166
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xlogp Value
|
1.0518
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Heavy Count
|
56
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Rot Bonds
|
26
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Hbond acc
|
14
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker