Linker Information
General Information of This Linker
| Linker ID |
LIN0VYRGY
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|---|---|---|---|---|---|---|
| Linker Name |
B-33 Linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H39N3O15
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| Isosmiles |
OCC1=CC=C(O[C@H](O2)[C@H](O)[C@@H](O)[C@H](O)[C@H]2C(O)=O)C(NC(CCNC(CCOCCOCCOCCN3C(C=CC3=O)=O)=O)=O)=C1
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| InChI |
InChI=1S/C29H39N3O15/c33-16-17-1-2-19(46-29-26(40)24(38)25(39)27(47-29)28(41)42)18(15-17)31-21(35)5-7-30-20(34)6-9-43-11-13-45-14-12-44-10-8-32-22(36)3-4-23(32)37/h1-4,15,24-27,29,33,38-40H,5-14,16H2,(H,30,34)(H,31,35)(H,41,42)/t24-,25-,26+,27-,29+/m0/s1
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| InChIKey |
KSBMCMFMQMUASS-DYXRGMLLSA-N
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| Pharmaceutical Properties |
Molecule Weight
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669.637
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Polar area
|
259.95
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Complexity
|
1200.425096
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xlogp Value
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-2.7404
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Heavy Count
|
47
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Rot Bonds
|
20
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Hbond acc
|
14
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker