Linker Information
General Information of This Linker
| Linker ID |
LIN0VVSAN
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| Linker Name |
CN114306633A-A-1-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C49H56N6O13S2
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| Isosmiles |
CC([C@H](NC(COCCOCCOCCOC1=CC=C(N2C(C(SC3=CC=CC=C3)=C(SC4=CC=CC=C4)C2=O)=O)C=C1)=O)C(N[C@@H](CCCNC(N)=O)C(NC5=CC=C(C=C5)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C49H56N6O13S2/c1-32(2)41(45(58)53-39(14-9-23-51-48(50)61)44(57)52-34-17-15-33(16-18-34)30-68-49(62)63)54-40(56)31-66-27-26-64-24-25-65-28-29-67-36-21-19-35(20-22-36)55-46(59)42(69-37-10-5-3-6-11-37)43(47(55)60)70-38-12-7-4-8-13-38/h3-8,10-13,15-22,32,39,41H,9,14,23-31H2,1-2H3,(H,52,57)(H,53,58)(H,54,56)(H,62,63)(H3,50,51,61)/t39-,41-/m0/s1
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| InChIKey |
ZOQKFXYZTJTKBT-WCAWKSPSSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1001.15
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Polar area
|
263.25
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Complexity
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2258.348716
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xlogp Value
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5.692
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Heavy Count
|
70
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Rot Bonds
|
29
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Hbond acc
|
14
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker