Linker Information
General Information of This Linker
| Linker ID |
LIN0VSQEM
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Conjugate No.46 Linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C30H48N6O12
|
|||||
| Isosmiles |
CC([C@H](NC([C@H](CCC(O)=O)NC(CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)=O)C(N[C@@H](CCCCN)C(O)=O)=O)C
|
|||||
| InChI |
InChI=1S/C30H48N6O12/c1-19(2)27(29(44)34-21(30(45)46)5-3-4-12-31)35-28(43)20(6-9-26(41)42)33-23(38)11-15-47-17-18-48-16-13-32-22(37)10-14-36-24(39)7-8-25(36)40/h7-8,19-21,27H,3-6,9-18,31H2,1-2H3,(H,32,37)(H,33,38)(H,34,44)(H,35,43)(H,41,42)(H,45,46)/t20-,21-,27-/m0/s1
|
|||||
| InChIKey |
ASNBGEFYORMEQR-IZVMNLJQSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
684.744
|
Polar area
|
272.86
|
||
|
Complexity
|
1080.859965
|
xlogp Value
|
-1.9702
|
|||
|
Heavy Count
|
48
|
Rot Bonds
|
26
|
|||
|
Hbond acc
|
11
|
Hbond Donor
|
7
|
|||
Each Antibody-drug Conjugate Related to This Linker