Linker Information
General Information of This Linker
| Linker ID |
LIN0VQJHJ
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| Linker Name |
Daratumumab-I-26--0.1 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C58H89FN14O18
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| Isosmiles |
FC1=CC=C(OC(CC[C@@H](NC(CCOCCOCCOCCOCCOCCOCCN)=O)C(NCCOCCOCCC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N/C(C(O)=O)=C/C2=CNC3=C2C=CC=C3)=O)=O)CCCNC(N)=N)=O)=O)=O)=O)C=C1
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| InChI |
InChI=1S/C58H89FN14O18/c59-41-9-11-42(12-10-41)91-52(77)14-13-47(71-50(75)16-22-84-26-29-87-31-33-89-35-36-90-34-32-88-30-27-85-23-17-60)53(78)65-20-24-86-28-25-83-21-15-49(74)70-46(8-4-19-67-58(63)64)55(80)73-45(7-3-18-66-57(61)62)54(79)69-39-51(76)72-48(56(81)82)37-40-38-68-44-6-2-1-5-43(40)44/h1-2,5-6,9-12,37-38,45-47,68H,3-4,7-8,13-36,39,60H2,(H,65,78)(H,69,79)(H,70,74)(H,71,75)(H,72,76)(H,73,80)(H,81,82)(H4,61,62,66)(H4,63,64,67)/b48-37+/t45-,46-,47+/m0/s1
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| InChIKey |
KYGLPTBJAXGIOZ-DVSJUHIMSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1289.428
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Polar area
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477.65
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Complexity
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2600.434708
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xlogp Value
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-1.68046
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Heavy Count
|
91
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Rot Bonds
|
52
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Hbond acc
|
20
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Hbond Donor
|
15
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Each Antibody-drug Conjugate Related to This Linker