Linker Information
General Information of This Linker
| Linker ID |
LIN0VNMUQ
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| Linker Name |
Ala-Phe linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C14H17BrN2O4
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| Isosmiles |
OC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC(CBr)=O)=O)=O
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| InChI |
InChI=1S/C14H17BrN2O4/c1-9(16-12(18)8-15)13(19)17-11(14(20)21)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H,16,18)(H,17,19)(H,20,21)/t9-,11-/m0/s1
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| InChIKey |
HZJZJIMIEOXDKD-ONGXEEELSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
357.204
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Polar area
|
95.5
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Complexity
|
478.0195914
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xlogp Value
|
0.6981
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Heavy Count
|
21
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Rot Bonds
|
7
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Hbond acc
|
3
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker