Linker Information
General Information of This Linker
| Linker ID |
LIN0VLKBW
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
IG-L-54 linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C53H76FN13O19
|
|||||
| Isosmiles |
CC(NC(C(NC(CCC1=CC=C(N2C(C=CC2=O)=O)C(F)=C1OCCCC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(O)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)C)=O)C(O)=O
|
|||||
| InChI |
InChI=1S/C53H76FN13O19/c1-32(52(83)56-33(2)53(84)85)55-36(68)18-16-34-15-17-35(67-38(70)19-20-39(67)71)50(54)51(34)86-21-13-14-37(69)57(3)22-40(72)58(4)23-41(73)59(5)24-42(74)60(6)25-43(75)61(7)26-44(76)62(8)27-45(77)63(9)28-46(78)64(10)29-47(79)65(11)30-48(80)66(12)31-49(81)82/h15,17,19-20,32-33H,13-14,16,18,21-31H2,1-12H3,(H,55,68)(H,56,83)(H,81,82)(H,84,85)
|
|||||
| InChIKey |
OBDCVBWQCIISKO-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
1218.261
|
Polar area
|
382.51
|
||
|
Complexity
|
2694.446933
|
xlogp Value
|
-4.8907
|
|||
|
Heavy Count
|
86
|
Rot Bonds
|
33
|
|||
|
Hbond acc
|
17
|
Hbond Donor
|
4
|
|||
Each Antibody-drug Conjugate Related to This Linker