Linker Information
General Information of This Linker
| Linker ID |
LIN0VKVDT
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| Linker Name |
MC-Val-Cit-RG-10
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C43H59N9O11
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| Isosmiles |
O=C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(NCC2=CC=CC=C2N(CCN3CCOCC3)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O
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| InChI |
InChI=1S/C43H59N9O11/c1-29(2)38(49-35(53)12-4-3-7-20-52-36(54)17-18-37(52)55)40(57)48-33(10-8-19-45-41(44)58)39(56)47-32-15-13-30(14-16-32)28-63-42(59)46-27-31-9-5-6-11-34(31)51(43(60)61)22-21-50-23-25-62-26-24-50/h5-6,9,11,13-18,29,33,38H,3-4,7-8,10,12,19-28H2,1-2H3,(H,46,59)(H,47,56)(H,48,57)(H,49,53)(H,60,61)(H3,44,45,58)/t33-,38-/m0/s1
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| InChIKey |
IPRIFDJSUBBBIE-BAOFOTJISA-N
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| Pharmaceutical Properties |
Molecule Weight
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877.997
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Polar area
|
271.14
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Complexity
|
1841.914291
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xlogp Value
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2.4276
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Heavy Count
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63
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Rot Bonds
|
24
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker