Linker Information
General Information of This Linker
| Linker ID |
LIN0VKQGV
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| Linker Name |
BVP-PEG3-carbamate-PEG4
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| Linker Type |
Flexible dual-reactive (thiol) linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H58N8O15S2
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| Isosmiles |
C=CS(=O)(=O)N1CCN(S(=O)(=O)C=C)C(C(=O)NCc2cn(CCOCCOCCOCC(=O)N(C)CCN(CCOCCOCCOCCOC)C(=O)O)nn2)C1
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| InChI |
InChI=1S/C33H58N8O15S2/c1-5-57(46,47)40-9-10-41(58(48,49)6-2)30(27-40)32(43)34-25-29-26-39(36-35-29)12-14-52-18-20-55-23-24-56-28-31(42)37(3)7-8-38(33(44)45)11-13-51-17-19-54-22-21-53-16-15-50-4/h5-6,26,30H,1-2,7-25,27-28H2,3-4H3,(H,34,43)(H,44,45)
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| InChIKey |
VMDHVRXABWPHLJ-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
871.002
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Polar area
|
260.03
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Complexity
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58
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xlogp Value
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-1.9885
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Heavy Count
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58
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Rot Bonds
|
33
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Hbond acc
|
17
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker
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