Linker Information
General Information of This Linker
| Linker ID |
LIN0VJIKW
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
IG-L-13 linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C21H24N4O8
|
|||||
| Isosmiles |
C[C@H](NC([C@@H](NC(CCN1C(C=CC1=O)=O)=O)C)=O)C(NC2=CC=C(C=C2)COC(O)=O)=O
|
|||||
| InChI |
InChI=1S/C21H24N4O8/c1-12(22-16(26)9-10-25-17(27)7-8-18(25)28)19(29)23-13(2)20(30)24-15-5-3-14(4-6-15)11-33-21(31)32/h3-8,12-13H,9-11H2,1-2H3,(H,22,26)(H,23,29)(H,24,30)(H,31,32)/t12-,13-/m0/s1
|
|||||
| InChIKey |
PTKWWAHRJLMDRM-STQMWFEESA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
460.443
|
Polar area
|
171.21
|
||
|
Complexity
|
912.7553347
|
xlogp Value
|
0.1442
|
|||
|
Heavy Count
|
33
|
Rot Bonds
|
10
|
|||
|
Hbond acc
|
7
|
Hbond Donor
|
4
|
|||
Each Antibody-drug Conjugate Related to This Linker