Linker Information
General Information of This Linker
| Linker ID |
LIN0VIJQS
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| Linker Name |
IG-L-65 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C15H11F3N2O4
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| Isosmiles |
FC(F)(F)C1(C2=CC(N3C(C=CC3=O)=O)=CC(NC(O)=O)=C2)CC1
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| InChI |
InChI=1S/C15H11F3N2O4/c16-15(17,18)14(3-4-14)8-5-9(19-13(23)24)7-10(6-8)20-11(21)1-2-12(20)22/h1-2,5-7,19H,3-4H2,(H,23,24)
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| InChIKey |
NJMGLEKUZHVPQI-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
340.257
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Polar area
|
86.71
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Complexity
|
726.7332564
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xlogp Value
|
2.7998
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Heavy Count
|
24
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Rot Bonds
|
3
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Hbond acc
|
3
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker