Linker Information
General Information of This Linker
| Linker ID |
LIN0VFOKI
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
CN112341521B+Linker12
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C43H67N7O18S
|
|||||
| Isosmiles |
CS(C1=NC(CN2CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@@H](CCCCN)C(NC3=CC=C(COC(O)=O)C=C3)=O)=O)=O)=C(C2=O)C=N1)(=O)=O
|
|||||
| InChI |
InChI=1S/C43H67N7O18S/c1-69(57,58)42-46-28-35-37(49-42)29-50(41(35)54)11-13-60-15-17-62-19-21-64-23-25-66-27-26-65-24-22-63-20-18-61-16-14-59-12-10-45-38(51)31-67-32-39(52)48-36(4-2-3-9-44)40(53)47-34-7-5-33(6-8-34)30-68-43(55)56/h5-8,28,36H,2-4,9-27,29-32,44H2,1H3,(H,45,51)(H,47,53)(H,48,52)(H,55,56)/t36-/m0/s1
|
|||||
| InChIKey |
XBEYHIMIYOMBCP-BHVANESWSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
1002.107
|
Polar area
|
323.15
|
||
|
Complexity
|
1839.077956
|
xlogp Value
|
-0.4514
|
|||
|
Heavy Count
|
69
|
Rot Bonds
|
41
|
|||
|
Hbond acc
|
20
|
Hbond Donor
|
5
|
|||
Each Antibody-drug Conjugate Related to This Linker