Linker Information
General Information of This Linker
| Linker ID |
LIN0VDDHG
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Antibody-drug conjugate (1)Linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C23H28N4O7
|
|||||
| Isosmiles |
O=C(N1CCCCCC(NCC(NCC(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)=O)C=CC1=O
|
|||||
| PubChem CID | ||||||
| InChI |
InChI=1S/C23H28N4O7/c28-18(9-5-2-6-12-27-21(31)10-11-22(27)32)24-14-19(29)25-15-20(30)26-17(23(33)34)13-16-7-3-1-4-8-16/h1,3-4,7-8,10-11,17H,2,5-6,9,12-15H2,(H,24,28)(H,25,29)(H,26,30)(H,33,34)/t17-/m0/s1
|
|||||
| InChIKey |
NFVPAFLSJIPUCL-KRWDZBQOSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
472.498
|
Polar area
|
161.98
|
||
|
Complexity
|
886.6165181
|
xlogp Value
|
-0.4837
|
|||
|
Heavy Count
|
34
|
Rot Bonds
|
14
|
|||
|
Hbond acc
|
6
|
Hbond Donor
|
4
|
|||
Each Antibody-drug Conjugate Related to This Linker