Linker Information
General Information of This Linker
| Linker ID |
LIN0VAYMW
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| Linker Name |
Coumpound17
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H42N6O10
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| Isosmiles |
O=C(NCC(NCC(N[C@H](C(NCC(N1C(OCC(O)=O)CCC1)=O)=O)CC2=CC=CC=C2)=O)=O)C(CC3)CCC3CN4C(C=CC4=O)=O
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| InChI |
InChI=1S/C33H42N6O10/c40-25(16-35-32(47)23-10-8-22(9-11-23)19-39-27(42)12-13-28(39)43)34-17-26(41)37-24(15-21-5-2-1-3-6-21)33(48)36-18-29(44)38-14-4-7-30(38)49-20-31(45)46/h1-3,5-6,12-13,22-24,30H,4,7-11,14-20H2,(H,34,40)(H,35,47)(H,36,48)(H,37,41)(H,45,46)/t22?,23?,24-,30?/m0/s1
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| InChIKey |
LVMFGXGQGHXNBK-PDXONNIISA-N
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| Pharmaceutical Properties |
Molecule Weight
|
682.731
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Polar area
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220.62
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Complexity
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1364.342704
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xlogp Value
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-1.1564
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Heavy Count
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49
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Rot Bonds
|
16
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Hbond acc
|
9
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker