Linker Information
General Information of This Linker
| Linker ID |
LIN0UWXQI
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| Linker Name |
IG-L-1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H40N6O9
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| Isosmiles |
CC(C(NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(O)=O)C=C2)=O)=O)C
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| InChI |
InChI=1S/C29H40N6O9/c1-18(2)25(34-22(36)8-4-3-5-16-35-23(37)13-14-24(35)38)27(40)33-21(7-6-15-31-28(30)41)26(39)32-20-11-9-19(10-12-20)17-44-29(42)43/h9-14,18,21,25H,3-8,15-17H2,1-2H3,(H,32,39)(H,33,40)(H,34,36)(H,42,43)(H3,30,31,41)/t21-,25?/m0/s1
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| InChIKey |
XZQPPZBBPOUVMS-BWDMCYIDSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
616.672
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Polar area
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226.33
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Complexity
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1158.897312
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xlogp Value
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1.3792
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Heavy Count
|
44
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Rot Bonds
|
18
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker