Linker Information
General Information of This Linker
| Linker ID |
LIN0UWXOR
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| Linker Name |
CN108853514B-Cet-8E-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H36N6O9
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| Isosmiles |
O=C(N/C=C/CC(O)=O)CNC([C@@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O
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| InChI |
InChI=1S/C29H36N6O9/c36-22(10-5-2-6-15-35-26(40)12-13-27(35)41)31-17-24(38)32-19-25(39)34-21(16-20-8-3-1-4-9-20)29(44)33-18-23(37)30-14-7-11-28(42)43/h1,3-4,7-9,12-14,21H,2,5-6,10-11,15-19H2,(H,30,37)(H,31,36)(H,32,38)(H,33,44)(H,34,39)(H,42,43)/b14-7+/t21-/m0/s1
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| InChIKey |
LQYGXKXYJJGEDT-MYHKYFONSA-N
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| Pharmaceutical Properties |
Molecule Weight
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612.64
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Polar area
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220.18
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Complexity
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1205.840307
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xlogp Value
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-1.3475
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Heavy Count
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44
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Rot Bonds
|
19
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker