Linker Information
General Information of This Linker
| Linker ID |
LIN0UVCFX
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| Linker Name |
Daratumumab-I-20-0.72 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C68H109N11O24S2
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| Isosmiles |
CON(C)C(CC[C@H](NC(CCCNC(C1=CC(NC(C2=CN(C=CS3)C3=N2)=O)=CC=C1OC)=O)=O)C(CCCOCCOCCOCCOCCOCCOCCOCCOCCN(C(OC[C@H]4[C@@H]5CCC(N6CCOCCOCCOCCOCCN)=C(N=N6)CC[C@H]45)=O)CCCS(O)(=O)=O)=O)=O
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| InChI |
InChI=1S/C68H109N11O24S2/c1-76(90-3)64(82)16-13-58(72-63(81)8-4-18-70-65(83)55-49-52(9-15-62(55)89-2)71-66(84)59-50-78-22-47-104-67(78)73-59)61(80)7-5-23-91-27-31-95-35-39-99-41-43-101-45-46-102-44-42-100-40-38-97-33-29-93-25-20-77(19-6-48-105(86,87)88)68(85)103-51-56-53-10-12-57-60(14-11-54(53)56)79(75-74-57)21-26-94-30-34-98-37-36-96-32-28-92-24-17-69/h9,15,22,47,49-50,53-54,56,58H,4-8,10-14,16-21,23-46,48,51,69H2,1-3H3,(H,70,83)(H,71,84)(H,72,81)(H,86,87,88)/t53-,54+,56+,58-/m0/s1
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| InChIKey |
ASYHSADMHHCXLG-WUOUWEMYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1528.807
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Polar area
|
411.84
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Complexity
|
3085.536525
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xlogp Value
|
2.7079
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Heavy Count
|
105
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Rot Bonds
|
62
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Hbond acc
|
30
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker