Linker Information
General Information of This Linker
| Linker ID |
LIN0UURWI
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| Linker Name |
ADCProductionexampleNo.10Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Formula |
C27H24FN3O7
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| Isosmiles |
CC[C@@](C(C=C1C2=NC(C=C(F)C(C)=C3CC[C@@H]4NC(C)=O)=C3C4=C2CN1C5=O)=C5CO6)(OC(O)=O)C6=O
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| InChI |
InChI=1S/C27H24FN3O7/c1-4-27(38-26(35)36)16-7-20-23-14(9-31(20)24(33)15(16)10-37-25(27)34)22-18(29-12(3)32)6-5-13-11(2)17(28)8-19(30-23)21(13)22/h7-8,18H,4-6,9-10H2,1-3H3,(H,29,32)(H,35,36)/t18-,27-/m0/s1
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| InChIKey |
PHGLRHIUJCFHLX-MYUZEXMDSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
521.501
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Polar area
|
136.82
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Complexity
|
1631.464712
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xlogp Value
|
3.35282
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Heavy Count
|
38
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Rot Bonds
|
3
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Hbond acc
|
8
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker