Linker Information
General Information of This Linker
| Linker ID |
LIN0UOXWM
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
CN119630431A-ADC-23-LINKER
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C34H37N3O8S2
|
|||||
| Isosmiles |
O=C(N1CCOCCOCCC(N[C@H](C(NCC(O)=O)=O)CC2=CCCC=C2)=O)C(SC3=CC=CC=C3)=C(SC4=CC=CC=C4)C1=O
|
|||||
| InChI |
InChI=1S/C34H37N3O8S2/c38-28(36-27(32(41)35-23-29(39)40)22-24-10-4-1-5-11-24)16-18-44-20-21-45-19-17-37-33(42)30(46-25-12-6-2-7-13-25)31(34(37)43)47-26-14-8-3-9-15-26/h2-4,6-15,27H,1,5,16-23H2,(H,35,41)(H,36,38)(H,39,40)/t27-/m0/s1
|
|||||
| InChIKey |
UZZMNWGTFJUFCI-MHZLTWQESA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
679.817
|
Polar area
|
151.34
|
||
|
Complexity
|
1390.896425
|
xlogp Value
|
3.9268
|
|||
|
Heavy Count
|
47
|
Rot Bonds
|
19
|
|||
|
Hbond acc
|
9
|
Hbond Donor
|
3
|
|||
Each Antibody-drug Conjugate Related to This Linker