Linker Information
General Information of This Linker
| Linker ID |
LIN0UOIOX
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| Linker Name |
CN106714844B-ADC-124-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C13H18N4O6S2
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| Isosmiles |
CN(CCN(C)C(OCCSSC1=NC=C([N+]([O-])=O)C=C1)=O)C(O)=O
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| InChI |
InChI=1S/C13H18N4O6S2/c1-15(12(18)19)5-6-16(2)13(20)23-7-8-24-25-11-4-3-10(9-14-11)17(21)22/h3-4,9H,5-8H2,1-2H3,(H,18,19)
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| InChIKey |
OQIDTCGJEAVUET-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
390.443
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Polar area
|
126.11
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Complexity
|
558.2060363
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xlogp Value
|
2.4083
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Heavy Count
|
25
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Rot Bonds
|
9
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Hbond acc
|
8
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Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker