Linker Information
General Information of This Linker
| Linker ID |
LIN0UKWEA
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| Linker Name |
L7-P2 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C50H79N7O21
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| Isosmiles |
CC([C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C(CN(C(CCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)C)=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C50H79N7O21/c1-36(2)46(55-41(58)10-15-69-18-14-57-43(60)8-9-44(57)61)48(65)54-40(5-4-13-52-49(51)66)47(64)53-39-7-6-37(35-78-50(67)68)38(33-39)34-56(3)42(59)11-16-70-19-21-72-23-25-74-27-29-76-31-32-77-30-28-75-26-24-73-22-20-71-17-12-45(62)63/h6-9,33,36,40,46H,4-5,10-32,34-35H2,1-3H3,(H,53,64)(H,54,65)(H,55,58)(H,62,63)(H,67,68)(H3,51,52,66)/t40-,46-/m0/s1
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| InChIKey |
SHYNCMHHDIZYKZ-QBPIONHWSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1114.21
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Polar area
|
367.01
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Complexity
|
1914.039085
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xlogp Value
|
0.1815
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Heavy Count
|
78
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Rot Bonds
|
47
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Hbond acc
|
19
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker