Linker Information
General Information of This Linker
| Linker ID |
LIN0UJZNU
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| Linker Name |
Mc-Val-Cit-PAB (Qamine) linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H33BrN4O5
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| Isosmiles |
C[C@H](NC([C@@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(C)C)=O)C(NC2=CC=C(CBr)C=C2)=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C25H33BrN4O5/c1-16(2)23(29-20(31)7-5-4-6-14-30-21(32)12-13-22(30)33)25(35)27-17(3)24(34)28-19-10-8-18(15-26)9-11-19/h8-13,16-17,23H,4-7,14-15H2,1-3H3,(H,27,35)(H,28,34)(H,29,31)/t17-,23-/m0/s1
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| InChIKey |
MXWUPZPZOJGJEU-SBUREZEXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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549.466
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Polar area
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124.68
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Complexity
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899.2899266
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xlogp Value
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2.6509
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Heavy Count
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35
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Rot Bonds
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13
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Hbond acc
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5
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Hbond Donor
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3
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Each Antibody-drug Conjugate Related to This Linker