Linker Information
General Information of This Linker
| Linker ID |
LIN0UJHWW
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| Linker Name |
CN113549127A-ADC-16-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C43H70N10O15S
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| Isosmiles |
OC([C@@H](NC([C@H](NC(OCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN1C=C(N=N1)CCCC#CC(C=N2)=CN=C2S)=O)=O)C(C)C)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C43H70N10O15S/c1-33(2)38(39(55)49-36(40(56)57)9-6-10-46-41(44)58)50-43(59)68-32-37(54)45-11-13-60-15-17-62-19-21-64-23-25-66-27-28-67-26-24-65-22-20-63-18-16-61-14-12-53-31-35(51-52-53)8-5-3-4-7-34-29-47-42(69)48-30-34/h29-31,33,36,38H,3,5-6,8-28,32H2,1-2H3,(H,45,54)(H,49,55)(H,50,59)(H,56,57)(H3,44,46,58)(H,47,48,69)/t36-,38+/m0/s1
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| InChIKey |
UEGYDOBKSHIXCW-KLESUSOLSA-N
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| Pharmaceutical Properties |
Molecule Weight
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999.155
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Polar area
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319.28
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Complexity
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1689.365416
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xlogp Value
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-0.2511
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Heavy Count
|
69
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Rot Bonds
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41
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Hbond acc
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20
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Hbond Donor
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7
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Each Antibody-drug Conjugate Related to This Linker