Linker Information
General Information of This Linker
| Linker ID |
LIN0UINDZ
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| Linker Name |
DIBAC-suC-PEG8
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C38H53N5O12
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| Isosmiles |
O=C(N(C(C=CC=C1)=C1C2=C3NN=N2)CC4=C3C=CC=C4)CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O
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| InChI |
InChI=1S/C38H53N5O12/c44-34(9-10-35(45)43-29-30-5-1-2-6-31(30)37-38(41-42-40-37)32-7-3-4-8-33(32)43)39-12-14-49-16-18-51-20-22-53-24-26-55-28-27-54-25-23-52-21-19-50-17-15-48-13-11-36(46)47/h1-8H,9-29H2,(H,39,44)(H,46,47)(H,40,41,42)
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| InChIKey |
NPGVAMFRDIKHAH-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
771.865
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Polar area
|
202.12
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Complexity
|
1493.435924
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xlogp Value
|
2.4892
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Heavy Count
|
55
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Rot Bonds
|
30
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Hbond acc
|
13
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker