Linker Information
General Information of This Linker
| Linker ID |
LIN0UFCOG
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| Linker Name |
CN112604004B-SCT-200-R-2-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H45N7O9
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC(C)C(N(CCC2)C2C(O)=O)=O)=O)=O)C
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| InChI |
InChI=1S/C29H45N7O9/c1-17(2)24(34-21(37)11-5-4-6-15-36-22(38)12-13-23(36)39)26(41)33-19(9-7-14-31-29(30)45)25(40)32-18(3)27(42)35-16-8-10-20(35)28(43)44/h12-13,17-20,24H,4-11,14-16H2,1-3H3,(H,32,40)(H,33,41)(H,34,37)(H,43,44)(H3,30,31,45)/t18?,19-,20?,24-/m0/s1
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| InChIKey |
JJYZKLQFIJACJO-DRMKDWESSA-N
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| Pharmaceutical Properties |
Molecule Weight
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635.719
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Polar area
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237.41
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Complexity
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1096.680551
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xlogp Value
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-0.8738
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Heavy Count
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45
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Rot Bonds
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18
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Hbond acc
|
8
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Hbond Donor
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6
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Each Antibody-drug Conjugate Related to This Linker