Linker Information
General Information of This Linker
| Linker ID |
LIN0UCAWE
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| Linker Name |
CN113549127A-ADC-11-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H47N7O9S
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| Isosmiles |
CCCSC1=NC=C(C(NCCCC(NCCOCCOCCNC(COCC(NC(C(O)=O)CCCCN)=O)=O)=O)=O)C=N1
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| InChI |
InChI=1S/C28H47N7O9S/c1-2-16-45-28-33-17-21(18-34-28)26(39)32-9-5-7-23(36)30-10-12-42-14-15-43-13-11-31-24(37)19-44-20-25(38)35-22(27(40)41)6-3-4-8-29/h17-18,22H,2-16,19-20,29H2,1H3,(H,30,36)(H,31,37)(H,32,39)(H,35,38)(H,40,41)
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| InChIKey |
PKVSFEAQMVDJSL-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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657.791
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Polar area
|
233.19
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Complexity
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954.2573837
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xlogp Value
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-0.5307
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Heavy Count
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45
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Rot Bonds
|
27
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Hbond acc
|
12
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker