Linker Information
General Information of This Linker
| Linker ID |
LIN0UBXLH
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| Linker Name |
Conjugate No.151 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C47H81N11O26
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| Isosmiles |
O=C(N1CCC(NCCOCCOCCC(NCC(NCC(NCC(NCC(NC(CO)C(NCCOCCC(NC(CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)O)C(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=O)=O)=O)=O)=O)C=CC1=O
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| InChI |
InChI=1S/C47H81N11O26/c59-23-27(57-39(73)22-54-38(72)21-53-37(71)20-52-36(70)19-51-34(68)6-11-83-15-16-84-13-8-48-33(67)5-10-58-40(74)3-4-41(58)75)47(81)49-9-14-82-12-7-35(69)56-26(46(80)55-18-29(63)43(77)45(79)31(65)25-61)1-2-32(66)50-17-28(62)42(76)44(78)30(64)24-60/h3-4,26-32,42-45,50,59-66,76-79H,1-2,5-25H2,(H,48,67)(H,49,81)(H,51,68)(H,52,70)(H,53,71)(H,54,72)(H,55,80)(H,56,69)(H,57,73)/t26?,27?,28-,29-,30+,31+,32?,42+,43+,44+,45+/m0/s1
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| InChIKey |
KEKGDVHUPJDDLC-APFGKTMASA-N
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| Pharmaceutical Properties |
Molecule Weight
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1216.216
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Polar area
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581.76
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Complexity
|
1981.723202
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xlogp Value
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-14.5332
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Heavy Count
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84
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Rot Bonds
|
47
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Hbond acc
|
27
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Hbond Donor
|
22
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Each Antibody-drug Conjugate Related to This Linker