Linker Information
General Information of This Linker
| Linker ID |
LIN0UBVXU
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
D1 Linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C20H32N6O6
|
|||||
| Isosmiles |
CC([C@H](NC(CON)=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)C
|
|||||
| InChI |
InChI=1S/C20H32N6O6/c1-12(2)17(26-16(28)11-32-22)19(30)25-15(4-3-9-23-20(21)31)18(29)24-14-7-5-13(10-27)6-8-14/h5-8,12,15,17,27H,3-4,9-11,22H2,1-2H3,(H,24,29)(H,25,30)(H,26,28)(H3,21,23,31)/t15-,17-/m0/s1
|
|||||
| InChIKey |
MPIYPINVBXWLJF-RDJZCZTQSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
452.512
|
Polar area
|
197.9
|
||
|
Complexity
|
727.8067451
|
xlogp Value
|
-0.9182
|
|||
|
Heavy Count
|
32
|
Rot Bonds
|
13
|
|||
|
Hbond acc
|
7
|
Hbond Donor
|
7
|
|||
Each Antibody-drug Conjugate Related to This Linker