Linker Information
General Information of This Linker
| Linker ID |
LIN0TYQDK
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|---|---|---|---|---|---|---|
| Linker Name |
LT4212552T-ADC-24-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H33N5O8
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| Isosmiles |
O=C(N1CCCCCC(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC2CC=CC=C2)=O)=O)=O)C=CC1=O
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| InChI |
InChI=1S/C25H33N5O8/c31-19(9-5-2-6-12-30-22(34)10-11-23(30)35)26-14-20(32)27-15-21(33)29-18(25(38)28-16-24(36)37)13-17-7-3-1-4-8-17/h1,3-4,7,10-11,17-18H,2,5-6,8-9,12-16H2,(H,26,31)(H,27,32)(H,28,38)(H,29,33)(H,36,37)/t17?,18-/m0/s1
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| InChIKey |
NSLIUIMMNCONFG-ZVAWYAOSSA-N
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| Pharmaceutical Properties |
Molecule Weight
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531.566
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Polar area
|
191.08
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Complexity
|
953.5084952
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xlogp Value
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-1.0878
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Heavy Count
|
38
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Rot Bonds
|
16
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Hbond acc
|
7
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker