Linker Information
General Information of This Linker
| Linker ID |
LIN0TYHCN
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| Linker Name |
CN119630431A-ADC-43-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H35N5O9S2
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| Isosmiles |
NC(C[C@@H](C(O)=O)NC(CCOCCOCCNC([C@@H](N1C(C(SC2=CC=CC=C2)=C(SC3=CC=CC=C3)C1=O)=O)CN)=O)=O)=O
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| InChI |
InChI=1S/C30H35N5O9S2/c31-18-22(27(38)33-12-14-44-16-15-43-13-11-24(37)34-21(30(41)42)17-23(32)36)35-28(39)25(45-19-7-3-1-4-8-19)26(29(35)40)46-20-9-5-2-6-10-20/h1-10,21-22H,11-18,31H2,(H2,32,36)(H,33,38)(H,34,37)(H,41,42)/t21-,22-/m0/s1
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| InChIKey |
LIFCJLFGMTZCFU-VXKWHMMOSA-N
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| Pharmaceutical Properties |
Molecule Weight
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673.77
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Polar area
|
220.45
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Complexity
|
1298.131381
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xlogp Value
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0.463
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Heavy Count
|
46
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Rot Bonds
|
20
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Hbond acc
|
11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker