Linker Information
General Information of This Linker
| Linker ID |
LIN0TUILF
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|---|---|---|---|---|---|---|
| Linker Name |
MC-Val-Ala-RG-1
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C35H44N6O9
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| Isosmiles |
O=C(N[C@@H](C)C(NC1=CC=C(COC(NCC2=CC=CC=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C35H44N6O9/c1-22(2)31(39-28(42)12-6-5-9-19-41-29(43)17-18-30(41)44)33(46)37-23(3)32(45)38-26-15-13-24(14-16-26)21-50-34(47)36-20-25-10-7-8-11-27(25)40(4)35(48)49/h7-8,10-11,13-18,22-23,31H,5-6,9,12,19-21H2,1-4H3,(H,36,47)(H,37,46)(H,38,45)(H,39,42)(H,48,49)/t23-,31-/m0/s1
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| InChIKey |
DMCKRTYYWOPACD-FWUCURJTSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
692.77
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Polar area
|
203.55
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Complexity
|
1514.491626
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xlogp Value
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3.2966
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Heavy Count
|
50
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Rot Bonds
|
17
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Hbond acc
|
8
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker