Linker Information
General Information of This Linker
| Linker ID |
LIN0TTSBO
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|---|---|---|---|---|---|---|
| Linker Name |
CN113453724B-ADCA-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H44N4O6
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| Isosmiles |
CN(C1=CC=C(CCN(C)[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)C(C)C)C=C1)C(CCCCCN2C(C=CC2=O)=O)=O
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| InChI |
InChI=1S/C30H44N4O6/c1-20(2)27(30(39)40)31-29(38)28(21(3)4)32(5)19-17-22-11-13-23(14-12-22)33(6)24(35)10-8-7-9-18-34-25(36)15-16-26(34)37/h11-16,20-21,27-28H,7-10,17-19H2,1-6H3,(H,31,38)(H,39,40)/t27-,28-/m0/s1
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| InChIKey |
MUXDXVSRJYGRCV-NSOVKSMOSA-N
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| Pharmaceutical Properties |
Molecule Weight
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556.704
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Polar area
|
127.33
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Complexity
|
1022.014179
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xlogp Value
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2.8591
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Heavy Count
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40
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Rot Bonds
|
16
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Hbond acc
|
6
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker