Linker Information
General Information of This Linker
| Linker ID |
LIN0TPNZI
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| Linker Name |
T-3 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H41N5O16S
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| Isosmiles |
O[C@@H]1[C@H](O)[C@@H](O)C(OC2=C(OS(=O)(O)=O)C=C(C(NCCOCCCN3C=C(N=N3)COCCOCCCN4C(C=CC4=O)=O)=O)C=C2)O[C@@H]1CO
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| InChI |
InChI=1S/C30H41N5O16S/c36-17-23-26(39)27(40)28(41)30(50-23)49-21-4-3-19(15-22(21)51-52(43,44)45)29(42)31-7-12-46-10-1-8-34-16-20(32-33-34)18-48-14-13-47-11-2-9-35-24(37)5-6-25(35)38/h3-6,15-16,23,26-28,30,36,39-41H,1-2,7-14,17-18H2,(H,31,42)(H,43,44,45)/t23-,26+,27+,28-,30?/m1/s1
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| InChIKey |
TWDGJSYHIKHEQZ-JZFOJYCBSA-N
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| Pharmaceutical Properties |
Molecule Weight
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759.744
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Polar area
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287.86
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Complexity
|
1544.989387
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xlogp Value
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-2.6766
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Heavy Count
|
52
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Rot Bonds
|
22
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Hbond acc
|
18
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker