Linker Information
General Information of This Linker
| Linker ID |
LIN0TOOQG
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| Linker Name |
CN113549127A-ADC-24-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C26H43N5O10
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| Isosmiles |
NCCCC[C@H](NC(COCC(NCCOCCOCCNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C26H43N5O10/c27-10-4-3-6-20(26(37)38)30-23(34)19-41-18-22(33)29-12-15-40-17-16-39-14-11-28-21(32)7-2-1-5-13-31-24(35)8-9-25(31)36/h8-9,20H,1-7,10-19,27H2,(H,28,32)(H,29,33)(H,30,34)(H,37,38)/t20-/m0/s1
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| InChIKey |
PDYAZANFQPZTPP-FQEVSTJZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
585.655
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Polar area
|
215.69
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Complexity
|
812.0996224
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xlogp Value
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-1.5476
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Heavy Count
|
41
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Rot Bonds
|
25
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Hbond acc
|
10
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker