Linker Information
General Information of This Linker
| Linker ID |
LIN0TJOHH
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|---|---|---|---|---|---|---|
| Linker Name |
Mal-Asn-Lys
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C19H31N7O6
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| Isosmiles |
NCCCCC(N)C(=O)NC(CC(N)=O)C(=O)NCCNC(=O)CCN1C(=O)C=CC1=O
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| InChI |
InChI=1S/C19H31N7O6/c20-7-2-1-3-12(21)18(31)25-13(11-14(22)27)19(32)24-9-8-23-15(28)6-10-26-16(29)4-5-17(26)30/h4-5,12-13H,1-3,6-11,20-21H2,(H2,22,27)(H,23,28)(H,24,32)(H,25,31)
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| InChIKey |
XTXHJSHXQXVMEO-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
453.5
|
Polar area
|
219.81
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Complexity
|
32
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xlogp Value
|
-3.6496
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Heavy Count
|
32
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Rot Bonds
|
15
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker
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