General Information of This Linker
Linker ID
LIN0TJGCF
Linker Name
Conjugate No.138 Linker
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C28H46N8O13
Isosmiles
O=C(N1CCC(NCCOCCOCCC(NCC(NCC(NCC(NCC(NC(CO)C(NCCOC)=O)=O)=O)=O)=O)=O)=O)CCC1=O
InChI
InChI=1S/C28H46N8O13/c1-47-10-6-30-28(46)19(18-37)35-25(43)17-34-24(42)16-33-23(41)15-32-22(40)14-31-21(39)5-9-48-12-13-49-11-7-29-20(38)4-8-36-26(44)2-3-27(36)45/h19,37H,2-18H2,1H3,(H,29,38)(H,30,46)(H,31,39)(H,32,40)(H,33,41)(H,34,42)(H,35,43)
InChIKey
RFEHKTZEKZHFOJ-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
702.719
Polar area
289
Complexity
1069.072168
xlogp Value
-6.2305
Heavy Count
49
Rot Bonds
26
Hbond acc
13
Hbond Donor
8
Each Antibody-drug Conjugate Related to This Linker