Linker Information
General Information of This Linker
| Linker ID |
LIN0TIOIN
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|---|---|---|---|---|---|---|
| Linker Name |
Daratumumab-I-37-5.49 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C59H95FN14O18
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| Isosmiles |
CC(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC1=CNC2=C1C=CC=C2)C(NCCOCCOCCOCCOCCNC(C3=CC=C(OC(CCOCCOCCOCCOCCOCCOCCN)=O)C(F)=C3)=O)=O)=O)=O)=O)CCCNC(N)=N)=O
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| InChI |
InChI=1S/C59H95FN14O18/c1-42(75)72-49(9-5-15-69-59(64)65)57(81)74-48(8-4-14-68-58(62)63)55(79)71-41-52(76)73-50(39-44-40-70-47-7-3-2-6-45(44)47)56(80)67-17-21-85-25-29-89-33-32-88-28-24-84-20-16-66-54(78)43-10-11-51(46(60)38-43)92-53(77)12-18-82-22-26-86-30-34-90-36-37-91-35-31-87-27-23-83-19-13-61/h2-3,6-7,10-11,38,40,48-50,70H,4-5,8-9,12-37,39,41,61H2,1H3,(H,66,78)(H,67,80)(H,71,79)(H,72,75)(H,73,76)(H,74,81)(H4,62,63,68)(H4,64,65,69)/t48-,49-,50-/m0/s1
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| InChIKey |
HKOJWPQDLCWMGB-HJENIEFXSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1307.487
|
Polar area
|
458.81
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Complexity
|
2518.933833
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xlogp Value
|
-2.06706
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Heavy Count
|
92
|
Rot Bonds
|
55
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Hbond acc
|
21
|
Hbond Donor
|
14
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Each Antibody-drug Conjugate Related to This Linker